Evaluation of inclusion exclusion criteria in clinical trial design 

 
   Lead Investigator:    Bradley T. Hyman
   Institution      :    Mass ADRC
   E-Mail           :    bhyman@partners.org
   Proposal ID      :    42


   Publications:


1  Ishihara-Paul L, Viswanathan A, Allen J, Hyman B, Betensky R, Weil J, Blacker D, Irizarry M
   P30 use of an US claims database and an US Alzheimer's Disease registry to assess clinical trial eligibility criteria
   Abstract  Health and Aging,12:543,2008,

   PUBLISHED





   Proposal Description:
   Specific Aims:   1. To estimate the impact of patient inclusion and exclusion criteria on patient recruitment for AD clinical trials.  2. To compare estimates of patient recruitment when eligibility criteria for a published clinical trial of rosiglitazone in AD (Risner ME, 2006) are applied a disease specific database (NACC), and a disease and site specific database (Massachusetts ADRC).